Endocytosis, cytoskeleton and cell migration

This team belongs to the UMR 1279 - Tumor cell dynamics

The overall objective of our lab is to understand how the mechanical properties of the tumoral environment influence cancer cell migration.

Team

Team leader

• Thomas MERCHER, DR2, INSERM
• Marie-Laure ARCANGELI, CRCN, INSERM

Members

• Muriel GAUDRY, CRCE, INSERM
• Hélène CAVE, PU-PH, Université Paris-Cité
• Marion STRULLU, MCU-PH, Université Paris-Cité
• Chloé ARFEUILLE, PH, Université Paris-Cité
• Charlotte RIGAUD, PH, Gustave Roussy
• Julie RIVIÈRE, IR, INSERM
• Zakia AID, Engineer
• Elie ROBERT, Bioinformatic engineer
• Kimberly TO, Engineer
• Mélanie VAR, Project Manager

Recent publications

• Fagnan A, Aid Z, Baille M, Drakul A, Robert E, Lopez CK, Thirant C, Lecluse Y, Rivière J, Ignacimouttou C, Salmoiraghi S, Anguita E, Naimo A, Marzac C, Pflumio F, Malinge S, Wichmann C, Huang Y, Lobry C, Chaumeil J, Soler E, Bourquin JP, Nerlov C, Bernard OA, Schwaller J, Mercher T. The ETO2 transcriptional co-factor maintains acute leukemia by driving a MYB/EP300-dependent stemness program.
  Hemasphere. 2024. in press

The team Biology of pediatric leukemia is part of the UMR 1170 Molecular dynamics of hematopoietic transformation.

Group : From haematopoietic stem cell to megakaryocyte

This group belongs to the UMR 1170 “Normal and pathological haematopoiesis”

Group TLS Polymerases: Genome Plasticity and Cancers

This group belongs to the team "TLS Polymerases: Genome Plasticity and Cancers" 

Hematopoietic transformation, epigenetic and transcription factors

This team belongs to the UMR 1170 Normal and pathologic haematopoiesis 

Lab members

• S Pitre-Champagnat Ch CNRS IGR
• N Lassau , PUPH IGR
• C Balleyguier, PH IGR
• F Bidault , PH doct IGR
• C Caramella, PH doct IGR
• S Ammary, PH doct IGR
• C Laplace-Builhé, Ch IGR
• M Abbaci, IR IGR
• I Leguerney, IR IGR
• A Volk, Ch INSERM
• B Benatsou, techn IGR
• MF Bellin , PUPH K Bicêtre
• S Franchi-Abella, PUPH K Bicêtre
• L Rocher , PUPH A Béclère
• A Castilla, PH A Béclère
• A Winkeler , IC CEA
• C Truillet, IC CEA

Major publications

Imaging PD-L1 Expression with ImmunoPET.
Truillet C, Oh HLJ, Yeo SP, Lee CY, Huynh LT, Wei J, Parker MFL, Blakely C, Sevillano N, Wang YH, Shen YS, Olivas V, Jami KM, Moroz A, Jego B, Jaumain E, Fong L, Craik CS, Chang AJ, Bivona TG, Wang CI, Evans MJ. Bioconjug Chem. 2018 Jan 17;29(1):96-103

Imaging in oncology

This team is attached to the BIOMAPS Unit.