Oncostat

Oncostat

This group is the Oncostat team of the UMR1018/CESP.

The Oncostat team develops methods for the evaluation of precision medicine in oncology based on the level of evidence.

UMR 1030

UMR 1030 - Molecular Radiotherapy and Therapeutic Innovation

UMR 1186

UMR 1186 - Integrative tumor immunology and immunotherapy

Our laboratory highlighted several constitutive elements of the tumor environment (TME) involved in the regulation of antitumor T-cell response, in particular:

UMR 1018/CESP

Centre for research in epidemiology and population health

The Centre for Research in Epidemiology and Population Health (CESP) is one of the largest French centres for training and research in Public Health.   

It is linked to Inserm, the Paris-Saclay University and the University of Versailles Saint Quentin.

3 of the CESP groups are based on the Gustave Roussy site:

Oncogenesis and tumour progression of melanoma - Lab members

Lab members

  • Brigitte Bressac de Paillerets, PhD, PharmD, Geneticist
  • Aude Robert, PhD, Research engineer
  • Justine Del Rio, Technician and lab manager
  • Julia Gilaizeau, Technician
  • Elisa Stubbs, PhD candidate
  • Sophie Lachaud, PhD candidate
  • Assaf Alassaf, M2
  • Mélanie Bennaroch, Technician

Oncogenesis and tumour progression of melanoma - Publications

Major publications

  • Golan, T., Parikh, R., Jacob, E., Vaknine, H., Zemser-Werner, V., Hershkovitz, D., Malcov, H., Leibou, S., Reichman, H., Sheinboim, D., Percik, R., Amar, S., Brenner, R., Greenberger, S., Kung, A., Khaled, M., and Levy, C. (2019) Adipocytes sensitize melanoma cells to environmental TGF-beta cues by repressing the expression of miR-211. Sci Signal 12

Oncogenesis and tumour progression of melanoma

Oncogenesis and tumour progression of melanoma group

This team belongs to the UMR 1279 - Tumor cell dynamics

In our group we are studying in parrallel:

  • The biology of melanocytes which are pigment producing cells responsible for skin color
  • The biology of cutaneous melanoma, which derives fromm melanocytes.

Using a comprehensive approach, we strive to identify mutations responsible for melanoma transformation and genes involved in metastasis.

UMR 1015

Tumour Immunology and anti-cancer immunotherapy unit

This unit is an Inserm, Gustave Roussy and Paris-Saclay University Mixed Research Unit.

The unit "Tumour immunology and anti-cancer immunotherapy" consists of two groups:

UMR 981

UMR 981 - Molecular predictors and new targets in oncology

Directed by Prof.Fabrice André, this Mixed Research Unit (Inserm - Gustave Roussy - University of Paris Sud) is a multiple team unit:

UMR 1170

UMR 1170 - Transcriptional and epigenetic control of Malignant Hematopoiesis

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