Vargas-Valderrama A. et al. Endothelial and hematopoietic hPSCs differentiation via a hematoendothelial progenitor. Stem Cell Res Ther. 2022 Jun 17;13(1):254.

Clinical Transfer Imaging - Activities

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Clinical Transfer Imaging - Activities

PFIC has the particularity to develop the transfer of photonic imaging for clinical applications in R&D division. R&D division is focused on the development of photonic tools mainly in collaborations with surgeons and pathologists to support tumor limits control, lymph nodes identification and flap perfusion viability. Our R&D division is engaged in ex vivo and in vivo clinical programs since 2008 with:

Cytometry and Imaging - Microscopy : recent publications

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Microscopy - recent publications

Endothelial and hematopoietic hPSCs differentiation via a hematoendothelial progenitor Alejandra Vargas‑Valderrama, Anne‑Charlotte Ponsen, Morgane Le Gall, Denis Clay, Sébastien Jacques, Tudor Manoliu, Valérie Rouffiac, Karine Ser‑le‑Roux, Cyril Quivoron, Fawzia Louache, Georges Uzan, Maria‑Teresa Mitjavila‑Garcia, Estelle Oberlin1† and Hind Guenou

Cytometry and Imaging - Microscopy : equipment

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Microscopy - Equipments

SP8 Confocal Microscope (Leica)

The system in reverse configuration is equipped with 4 lasers covering excitation wavelengths 405, 488, 561, and 638nm. Fluorescence signals are collected on 2 PMT detectors and 2 high-sensitivity HyD detectors. A thermostatic and CO2-regulated chamber and a motorized turntable are installed on the microscope for kinetic studies and XYZT acquisitions.

This microscope is suitable for confocal, wide-field and/or multi-position imaging.

Cytometry and Imaging - Microscopy : Activities

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Microscopy - Activities

Theoretical classes and practical training in photonic microscopy technics
Confocal and multiphoton imaging of cells and tissues
TIRF, live-SR, FRAP, FRET, Photoconversion, Optogenetics
Multidimensional dynamic imaging in living organs & 3D organoid models
Support for the development of new optical devices
Design of experimental procedures
Scientific animations
Technological developments and innovation
Imaging of organoid models

Chromatin function in DNA repair

CARE1: A European Study on First-Line Treatment of Metastatic Kidney Cancer

LySAIRI: towards an innovative radiotherapy that facilitates immune sparing to improve overall clinical efficacy

Laurie Menger

Biography

Clinical Transfer Imaging - Team members

Clinical Transfer Imaging - Recent publications

Clinical Transfer Imaging - Activities

Microscopy - recent publications

Microscopy - Equipments

SP8 Confocal Microscope (Leica)

Microscopy - Activities

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