SEAT - Collaborateurs

  • Gustave Roussy
  • CNRS
  • INSERM
  • ENS
  • Génopôle/Généthon Evry
  • Institut Pasteur
  • Université Pierre et Marie Curie

SEAT - Publications

PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice
Abramowski M, Etienne O, Elsaid R, Yang J, Berland A, Kermasson L, Roch B, Musilli S, Moussu JP, Lipson-Ruffert K, Revy P, Cumano A, Boussin FD, de Villartay JP Cell Death and Differentiation 2018.

Calibrated mitotic oscillator drives motile ciliogenesis
Al Jord A, Shihavuddin A, Servignat d’Aout R, Faucourt M, Genovesio A, Karaiskou A, Sobczak-Thépot J, Spassky N, Meunier A. Science 2017 (en remerciement).

SEAT

Le Service des Animaux Transgéniques a été ouvert au public en 1992 et fait partie des plateformes de Gustave Roussy (UMS 3655). Il est ouvert à tous les scientifiques, des secteurs publics et privés, désireux d'utiliser des techniques sophistiquées de modification du génome murin.

Pour répondre au mieux aux besoins des chercheurs, le SEAT comprend plusieurs services :

Scientific integrity

Scientific Integrity

Scientific integrity refers to the set of rules and values that must govern research activities to ensure that they are honest, impartial, objective and scientifically rigorous.

The Research Programming Act (LPR) of 2020 entrusted Hcéres (Haut Conseil à l'évaluation de la recherche et de l'enseignement supérieur) with new missions in the area of scientific integrity. Ofis (the French Office for Scientific Integrity) is responsible for implementing these missions.

CD8 T-cell immunity and immunotherapy in lung cancer

CD8 T-cell immunity and immunotherapy in lung cancer

This group belongs to the UMR 1186 - Integrative tumor immunology and immunotherapy

Despite advances in immunotherapy, a large fraction of cancer patients fails to respond. Immune mechanisms behind this resistance are poorly elucidated. The objective of our research program is to comprehensively characterize and study the role of a new class of white blood cells, called resident memory T cells (TRM), in antitumor immunity and response to cancer immunotherapy.

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