UMR 9018 - Metabolic and systemic aspects of oncogenesis for new therapeutic approaches (METSY)
Head of unit: Dr Catherine Brenner
The research program developped by the laboratory aim at the discovery and characterization of new targets for the treatment of cancers and the development of innovative therapeutic strategies (adenoviral vectors, nanoparticles, small molecules).
Three main scientific objectives are being pursued:
- to better understand the metabolic plasticity of cancer cells
- to characterise host-tumour interactions in head and neck carcinomas
- to study the dynamics of chromatin and metabolism in cancer, particularly in Burkitt lymphoma
This Research Unit is subdivided into three teams:
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Team 1, "Metabolic Plasticity in Health and Disease" headed by Catherine Brenner
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Team 2, "Host tumor interactions in Head and Neck Carcinoma : Exploration and therapeutic modulations" headed by Karim Benihoud
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Team 3, "Chromatin Dynamics and Metabolism in Cancer" headed by Yegor Vassetzky and Svetlana Dokudovskaya
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