Major publications

1: Muhammad AA, Basto C, Peterlini T, Guirouilh-Barbat J, Thomas M, Veaute X, Busso D, Lopez B, Mazon G, Le Cam E, Masson JY, Dupaigne P. Life Sci Alliance. 2023 Dec 11;7(3):e202201751. doi: 10.26508/lsa.202201751. Print 2024 Mar. PMID: 38081641

Double strand break repair and Genome Integrity Team

This team belongs to the UMR 9019 Genome Integrity and Cancers.

Lab members

• Murat SAPARBAEV, Research Director, DR1, CNRS;
• Alexandre A. ISHCHENKO, Research Director, DR2, CNRS;
• Regina GROISMAN, CRCN, INSERM;
• Sophie GAD-LAPITEAU, Professor, EPHE ;
• Sophie COUVE, Assistant professor, EPHE ;
• Flore RENAUD-PAITRA, Assistant professor, EPHE ;
• Sophie FERLICOT, PU-PH, clinicien, Université Paris-Saclay ;
• Dominique BLUTEAU, Assistant professor, EPHE ;
• Kévin BOQUET, technician, EPHE;
• Victoria POILLERAT, PhD student, EPHE;

Major publications

• Matkarimov, B.T., Zharkov, D.O., and SAPARBAEV, M.K. (2019) Mechanistic insight into the role of Poly(ADP-ribosyl)ation in DNA topology modulation and response to DNA damage. Mutagenesis, Nov 29. pii: gez045. doi: 10.1093/mutage/gez045/5646155.

Mechanisms of DNA Repair and Carcinogenesis

This team belongs to the UMR 9019 Genome Integrity and Cancers.

Lab members

Major Publications

• Oppezzo A, Bourseguin J, Renaud E, Pawlikowska P, Rosselli F. Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia. J Clin Invest. 2020, 130:1377-1391.
• Brison O, El-Hilali S, Azar D, Koundrioukoff S, Schmidt M, Nähse V, Jaszczyszyn Y, Lachages AM, Dutrillaux B, Thermes C, Debatisse M, Chen CL. Transcription-mediated organization of the replication initiation program across  large genes sets common fragile sites genome-wide. Nat Commun, 2019, 10:5693.

4Rs : Replication, Repair, Recombination and ROS

This team belongs to the UMR 9019 Genome Integrity and Cancers.

Lab members

• Saïd AOUFOUCHI – Research Scientist – Group Leader
• Dorine BONTE – Assistant professeur -Paris Sud University
• Léticia KOCH- LERNER- Post doc
• Morwenna Le GUILLOU – Engineer assistant Paris Sud University
• Céline DECAUX- Master2 trainer programm UPMC
• Charlène TRILLeaud - Master1 trainer programm UPMC
• Roukia BELGADAR Undergraduate student –UPMC

Major publications since 2009

• Xavier Renaudin, Jean-Hugues Guervilly, Said Aoufouchi, and Filippo Rosselli.Proteome-wide analysis unveils a FANCA-modulated neddylation signaling pathway involved in CXCR5 membrane trafficking and cell mobility. 
• J Cell Sci. 2014 Aug 15;127(Pt 16):3546-54. doi: 10.1242/jcs.150706. Epub 2014 Jul 11.