A research with strong societal impact integrated with care
Research at Gustave Roussy meets society's needs related to cancer. It is integrated into care because it is in the context of care that the data on which the research is based are collected from patients, and it is for the care of patients that the results of the research are used.
UMR 1186 - Integrative tumor immunology and immunotherapy
Our laboratory highlighted several constitutive elements of the tumor environment (TME) involved in the regulation of antitumor T-cell response, in particular:
Golan, T., Parikh, R., Jacob, E., Vaknine, H., Zemser-Werner, V., Hershkovitz, D., Malcov, H., Leibou, S., Reichman, H., Sheinboim, D., Percik, R., Amar, S., Brenner, R., Greenberger, S., Kung, A., Khaled, M., and Levy, C. (2019) Adipocytes sensitize melanoma cells to environmental TGF-beta cues by repressing the expression of miR-211. Sci Signal 12