Endocytose, cytosquelette et migration cellulaire

Publications majeures

• Lock JG, Baschieri F, Jones MC, Humphries JD, Montagnac G, Strömblad S, Humphries MJ. Clathrin-containing adhesion complexes. J Cell Biol. 2019 Jul 1;218(7):2086-2095. doi: 10.1083/jcb.201811160. Epub 2019 Jun 17.
• Baschieri F, Dayot S, Elkhatib N, Ly N, Capmany A, Schauer K, Betz T, Vignjevic DM, Poincloux R, Montagnac G. Frustrated endocytosis controls contractility-independent mechanotransduction at clathrin-coated structures. Nat Commun. 2018 Sep 20;9(1):3825. doi: 10.1038/s41467-018-06367-y.
• Elkhatib N, Montagnac G. Frustrated endocytosis supports 3D cell migration. Med Sci (Paris). 2018 Jun-Jul;34(6-7):522-524. doi: 10.1051/medsci/20183406009. Epub 2018 Jul 31.
• Janke C, Montagnac G. Causes and Consequences of Microtubule Acetylation. Curr Biol. 2017 Dec 4;27(23):R1287-R1292. doi: 10.1016/j.cub.2017.10.044.
• Elkhatib N, Bresteau E, Baschieri F, Rioja AL, van Niel G, Vassilopoulos S, Montagnac G. Tubular clathrin/AP-2 lattices pinch collagen fibers to support 3D cell migration. Science. 2017 Jun 16;356(6343). pii: eaal4713. doi: 10.1126/science.aal4713.
• De Franceschi N, Arjonen A, Elkhatib N, Denessiouk K, Wrobel AG, Wilson TA, Pouwels J, Montagnac G, Owen DJ, Ivaska J. Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2. Nat Struct Mol Biol. 2017 Feb 6;24(2):194. doi: 10.1038/nsmb0217-194b.
• Ly N, Elkhatib N, Bresteau E, Piétrement O, Khaled M, Magiera MM, Janke C, Le Cam E, Rutenberg AD, Montagnac G. αTAT1 controls longitudinal spreading of acetylation marks from open microtubules extremities. Sci Rep. 2016 Oct 18;6:35624. doi: 10.1038/srep35624.
• Marchesin V, Castro-Castro A, Lodillinsky C, Castagnino A, Cyrta J, Bonsang-Kitzis H, Fuhrmann L, Irondelle M, Infante E, Montagnac G, Reyal F, Vincent-Salomon A, Chavrier P. ARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion.J Cell Biol. 2015 Oct 26;211(2):339-58. doi: 10.1083/jcb.201506002.
• Boissan M, Montagnac G, Shen Q, Griparic L, Guitton J, Romao M, Sauvonnet N, Lagache T, Lascu I, Raposo G, Desbourdes C, Schlattner U, Lacombe ML, Polo S, van der Bliek AM, Roux A, Chavrier P. Membrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling. Science. 2014 Jun 27;344(6191):1510-5. doi: 10.1126/science.1253768.
• Montagnac G, Meas-Yedid V, Irondelle M, Castro-Castro A, Franco M, Shida T, Nachury MV, Benmerah A, Olivo-Marin JC, Chavrier P. αTAT1 catalyses microtubule acetylation at clathrin-coated pits. Nature. 2013 Oct 24;502(7472):567-70. doi: 10.1038/nature12571. Epub 2013 Oct 6