Fonction de la chromatine dans la réparation de l'ADN

Fonction de la chromatine dans la réparation de l'ADN

Publications récentes

• Giacomini G., Piquet S., Chevallier O., Dabin J., Bai S.-K., Kim B., Siddaway R., Raught B., Coyaud E., Shan C.-M., Reid R.J.D., Toda T., Rothstein R., Wilhelm T., Barra V., Crane A., Dubois F., Bandopadhayay P., Beroukhim R., Naim V., Jia S., Hawkins C., Rondinelli B.§ and Polo S. E.§ Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors, Nucleic Acids Res. 2024 Jan 12:gkad1257.  doi: 10.1093/nar/gkad1257.  Online ahead of print.
• Ferrand J.*, Rondinelli B.*, Polo S. Histone variants: guardians of genome integrity, Cells, 2020 Nov 5; 9(11):2424.
• Rondinelli B., Gogola E., Yücel H., Duarte A.A., van de Ven M., van der Sluijs R., Konstantinopoulos P.A., Jonkers J., Ceccaldi R., Rottenberg S., D’Andrea A.D. EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation, Nature Cell Biology, 2017 Nov; 19(11):1371-1378. *
• Kais Z.*, Rondinelli B.*, Holmes A., O'Leary C., Kozono D., D'Andrea A.D.§ and Ceccaldi R§. FANCD2 maintains fork stability in BRCA1/2-deficient tumors allowing for alternative end-joining DNA repair. Cell Reports, 2016 Jun 14 ; 15(11):2488-99.
• Ceccaldi R., Rondinelli B., D'Andrea A.D. Repair Pathway Choices and Consequences at the Double-Strand Break. Trends in Cell Biology, 2016 Jan; 26(1):52-64.
• Rondinelli B., Rosano D., Antonini E., Frenquelli M., Montanini L., Huang D., Segalla S., Yoshihara K., Amin S.B., Lazarevic D., Verhaak R.G., Futreal P.A., Di Croce L., Chin L., Cittaro D., Tonon G. Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer. Journal of Clinical Investigations, 2015 Dec; 125(12):4625-37.
• Rondinelli B., Schwerer H., Antonini E., Gaviraghi M., Lupi A., Frenquelli M., Cittaro D., Segalla S., Lemaitre J.M., Tonon G. H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firing. Nucleic Acids Research, 2015 Mar 11; 43(5):2560-74.