Espèces Réactives de l'Oxygène et Radiocarcinogenèse

Responsable
Dr Corinne Dupuy
Tél.: +33(0) 1 42 11 40 74
 

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Espèces Réactives de l'Oxygène et Radiocarcinogenèse

Publications (2010-2015)

  • Ameziane-El-Hassani R, Talbot M, de Souza Dos Santos MC, Al Ghuzlan A, Hartl D,  Bidart  JM, De Deken X, Miot F, Diallo I, de Vathaire F, Schlumberger M, Dupuy C. NADPH oxidase DUOX1 promotes long-term persistence of oxidative stress after an exposure to irradiation.
    Proc Natl Acad Sci U S A. 2015; 112(16):5051-6.
  • Carré A, Louzada RA, Fortunato RS, Ameziane-El-Hassani R, Morand S, Ogryzko V, de Carvalho DP, Grasberger H, Leto TL, Dupuy C When an Intramolecular Disulfide Bridge Governs the Interaction of DUOX2 with Its Partner DUOXA2.
    Antioxid Redox Signal. 2015 23(9):724-33
  • Ueyama T, Sakuma M, Ninoyu Y, Hamada T, Dupuy C, Geiszt M, Leto TL, Saito N. The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species  release.
    J Biol Chem. 2015 290(10):6495-506
  • Rousset F, Hazane-Puch F, Pinosa C, Nguyen MV, Grange L, Soldini A, Rubens-Duval B, Dupuy C, Morel F, Lardy B IL-1beta mediates MMP secretion and IL-1beta neosynthesis via upregulation of p22(phox) and NOX4 activity in human articular chondrocytes. Osteoarthritis Cartilage. 2015 23(11):1972-80.
  • Fortunato RS, Ferreira AC, Hecht F, Dupuy C, Carvalho DP. Sexual dimorphism and thyroid dysfunction: a matter of oxidative stress?
    J Endocrinol. 2014 221(2):R31-40. Review.
  • Weyemi U, Redon CE, Parekh PR, Dupuy C, Bonner WM. NADPH Oxidases NOXs and DUOXs as Putative Targets for Cancer Therapy.
    Anticancer Agents Med Chem. 2013 13(3):502-14.
  • Carvalho DP & Dupuy C. Role of the NADPH Oxidases DUOX and NOX4 in Thyroid  Oxidative Stress.
    Eur Thyroid J. 2013 2(3):160-7. Review.
  • Weyemi U, Lagent-Chevallier O, Boufraqech M, Prenois F, Courtin F, Caillou B, Talbot M, Daralhon M, Al Ghuzlan A, Bidart JM, Schlumberger M, Dupuy C. ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-RAS-induced DNA damage and subsequent senescence.
    Oncogene 2012 31: 1117-29
  • Weyemi U, Dupuy C The emerging role of ROS-generating NADPH oxidase NOX4 in DNA- damage responses. Mutat Res. 2012 751(2):77-81
  • Schlumberger M, Chevillard S, Ory K, Dupuy C, Le Guen B, de Vathaire F. Thyroid cancer following exposure to ionising radiation.
    Cancer Radiother. 2011 15: 394-9
  • Caillou B, Talbot M, Weyemi U, Pioche-Durieu C, Al Ghuzlan A, Bidart JM, Chouaib S, Schlumberger M, Dupuy C. Tumor-Associated Macrophages (TAMs) form an Interconnected Cellular Supportive Network in Anaplastic Thyroid Carcinoma.
    PloS One 2011, 6: e22567
  • Weyemi U, Caillou B, Talbot M, Ameziane-El-Hassani R, Lacroix L, Lagent-Chevallier O, Al Ghuzlan A, Roos D, Bidart JM, Virion A, Schlumberger M, Dupuy C. Intracellular  expression of reactive oxygen species-generating NADPH oxidase NOX4 in normal and cancer thyroid tissues.
    Endocr Relat Cancer. 2010 17:27-37.
  • Fortunato RS, Lima de Souza EC, Ameziane-el Hassani R, Boufraqech M, Weyemi U, Talbot M, Lagente-Chevallier O, de Carvalho DP, Bidart JM, Schlumberger M, Dupuy C. Functional consequences of dual oxidase-thyroperoxidase interaction at the plasma membrane.
    J Clin Endocrinol Metab. 2010 95: 5403-11
  • Ameziane-El-Hassani R, Boufraqech M, Lagente-Chevallier O, Weyemi U, Talbot M, Métivier D, Courtin F, Bidart JM, El Mzibri M, Schlumberger M and Dupuy C. Role of H2O2 in  RET/PTC1 chromosomal rearrangement produced by ionizing radiation in human thyroid cells.
    Cancer Res. 2010 70: 4123-32.
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